Ulcerated Pilomatrixoma: A Frequently Misdiagnosed Tumour

Abstract

Pilomatrixoma is a rare superficial benign skin tumor arising from the hair follicle matrix cells. Pilomatrixoma can occasionally become malignant.  Complete surgical excision is often curative. It is often clinically misdiagnosed, hence the reason to share this case. We report a case of a 19-year-old man who presented with an ulcerated non-painful swelling involving the medial part of the right upper eyelid for two years. It was initially clinically diagnosed as keratoacanthoma and later basal cell carcinoma. However, histopathological examination after complete surgical excision revealed features of pilomatrixoma. This report highlights that pilomatrixoma may be misdiagnosed in clinical practice.